The uncertainty of estimation of doses to the bone marrow from <sup>89,90</sup>Sr due to the variability of the chemical composition and bone density

Dosimetric modeling of radiation transport in skeletal bone tissues using computational phantoms provides the doses internal exposure to active marrow. Computational ICRP are created for reference people with anatomical and physiological characteristics typical an average individual. The calculated such will correspond certain population-average values. Individual variability introduce a stochastic component uncertainty into dose estimation. objective this study is assess influence chemical composition density on results dosimetric modeling. represented by simple geometry figures filled trabecular structures marrow covered cortical layer. Radiation was simulated Monte Carlo method. factors convert radionuclide activity concentration absorbed rates were assuming uniform distribution volume bone. As result numerical experiments, it has been shown that variations do not error more than ± 4% effect formation depends size phantom. For linear dimensions exceeding two electron free path lengths (~ 0.44 cm), within 3% leads similar relative conversion factor. However, smaller phantoms, uncertainties 6% or 13% source deposited bone, respectively. obtained be used dosimetry, taking account all parameters including morphometric bones, sites, as well introduced model approximations.